Hemicrania continua responds to cyclooxygenase-2 inhibitors.
نویسندگان
چکیده
BACKGROUND Hemicrania continua is a primary headache disorder defined by its absolute responsiveness to indomethacin. We report the treatment response to two cyclooxygenase-2 inhibitors, celecoxib and rofecoxib, in a series of patients with hemicrania continua. METHODS Fourteen patients were treated, 9 with rofecoxib and 5 with celecoxib. RESULTS Three patients in each group had a complete response to treatment. CONCLUSION The cyclooxygenase-2 inhibitors may represent an alternative to indomethacin in the treatment of hemicrania continua. Their mechanism of action for this potential indication is unknown.
منابع مشابه
Treatment of hemicrania continua: case series and literature review.
BACKGROUND AND OBJECTIVES Hemicrania Continua (HC) is a primary, disabling headache characterized by a continuous unilateral pain and responsive to indomethacin. There are symptoms common to the trigeminal-autonomic cephalalgias and migraine that complicate the diagnosis. This review aims to describe HC in a case series and review the best available evidence on alternative therapies. METHOD A...
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PURPOSE OF REVIEW This article covers the clinical manifestations and differential diagnosis of the trigeminal autonomic cephalalgias (TACs). RECENT FINDINGS TACs comprise a subgroup of primary headache disorders presenting with lateralized, often severe, pain accompanied by cranial autonomic features. The key syndromes are cluster headache, paroxysmal hemicrania, short-lasting unilateral neu...
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Hemicrania continua is a headache characterized by chronic unremitting unilateral pain associated with ipsilateral autonomic findings. This type of headache responds to high-flow oxygen and indomethacin. This case report describes a male veteran with posttraumatic stress disorder (PTSD) and major depressive disorder who suffers from comorbid hemicrania continua. The psychiatric symptoms were re...
متن کاملHemicrania Continua.
Hearing the diagnosis of hemicrania continua can seem as if the medical provider is stating the obvious, because the name in Latin means that half of the head hurts. However, hemicrania continua is a unique type of headache, one that by definition responds to 1 medication, indomethacin. Hemicrania continua is usually referred to by its initials, HC. While HC is not seen as frequently as migrain...
متن کاملMisdiagnosis of hemicrania continua.
Hemicrania continua (HC) is a primary headache disorder that is characterized by a continuous unilateral headache of moderate severity, exacerbations of severe pain, and complete responsiveness to indomethacin. Misdiagnosis of HC is probably common in general neurology settings and other clinical specialties. This paper is an attempt to bridge the gap between the correct and misdiagnosis of thi...
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ورودعنوان ژورنال:
- Headache
دوره 42 6 شماره
صفحات -
تاریخ انتشار 2002